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What is Morphine and when is it used?

Morphine is an analgesic used to treat moderate to severe chronic pain. Morphine is the primary active ingredient. After taking Morphine, the morphine enters the bloodstream and is absorbed slowly through the gastrointestinal tract.

If you must use morphine, get a prescription from your doctor and use it only under close medical supervision.

In the event that you are hypersensitive (allergic) to the active ingredient morphine or to one of its auxiliary ingredients, if you have severe breathing problems, such as shallow and slow breathing (severe respiratory depression), if you have severe chronic lung disease that has resulted in a narrowing of the airways (severe chronic obstructive pulmonary disease (COPD)), if you have acute abdominal pain, or if intestinal paralysis is present, you should not use this medication (paralytic ileus).
When is it necessary to exercise caution when administering Morphine?
A significant rise in the right heart's pressure following pulmonary hypertension (severe cor pulmonale), severe asthma or breathing problems, severe liver or renal insufficiency, hypothyroidism, adrenal insufficiency (Addison's disease), mental disorders caused by alcohol or from intoxication, alcoholism, or severe reactions to an alcohol detox,
You are more susceptible to side effects if you are older or physically weak. As a result, extra care should be taken.

MORPHINE Continus use for an extended period of time increases the risk of addiction. As a result, a higher dose may be required to produce the desired analgesic results.

Morphine use for an extended period of time can lead to physical dependence. Withdrawal symptoms such as restlessness, sweating, and muscle aches may occur if treatment is abruptly stopped. If you are no longer in need of treatment, you should gradually reduce the daily dose in consultation with your doctor.

The abuse potential of morphine's active ingredient is the same as that of all other morphine-like strong pain relievers. There's a chance you could become addicted to your psychic abilities. The use of Morphine should be avoided if you are currently abusing any of these substances.

Tell your surgeon if you're taking Morphine if you're having surgery.

Continusit can cause reversible hormonal changes, such as decreased adrenal cortex function with symptoms like nausea, vomiting, loss of appetite, fatigue, weakness, dizziness, or arterial hypotension, or decreased sexual organ function with symptoms like decreased libido, erectile dysfunction or amenorrhea, when taken for an extended period of time. These changes are reversible.

Morphine has the potential to impair a person's ability to become pregnant.

Medication side effects (such as impaired respiratory function, hypotension, drowsiness, and/or reduced alertness) can be increased by some drugs, and these side effects can lead to death or serious injury in severe cases.

Some medications for allergies, motion sickness or nausea, some antidepressants and psychostimulants, some medicines to treat seizures and certain types of pain (e.g. phenytoin, gabapentin or pregabalin), muscle relaxants, and other morphine-like analgesics (opioids), sleeping pills and tranquilizers (such as benzodiazepines) (muscle relaxants).
If you're taking any of these medications, call your doctor or pharmacist right away.

If you're taking Morphine, avoid drinking alcohol. Alcohol consumption during MORPHINE Continus treatment can cause excessive sleepiness and increase the risk of side effects such as shallow breathing and the resulting risk of respiratory arrest and loss of consciousness, which can lead to coma and death in severe cases.

Morphine suspension retard should be taken at least 2 hours after taking an antiacid medicine (antacid).

It's possible that if you use Morphine, you'll test positive for doping.

Morphine can impair reaction time, driving skills, and the ability to operate machinery or tools. Consult your physician to see if you're still able to operate heavy machinery, drive a car, or perform other potentially hazardous tasks.

Lactose is present in the morphine retard tablets in dosages of 10 mg, 30 mg, and 60 mg. So, if you're sensitive to certain sugars, talk to your doctor before taking these doses of Morphine.

The use of Morphine 30 mg and 60 mg tablets retard and Morphine suspension retard should be avoided by patients who are allergic to azo dyes, acetylsalicylic acids, antirheumatics, or analgesics (prostaglandin inhibitors).

Assert yourself with your doctor or pharmacist if you have any other health issues, allergies, and/or medications that you use or have used in the past.

Can Morphine be taken while pregnant or breastfeeding?


If MORPHINE Continus is used for an extended period of time while pregnant, the baby may experience withdrawal symptoms. If Morphine is used during childbirth, the newborn may experience respiratory depression, which is characterized by a slowing and flattening of the breath. Pregnant women should not be given morphine. Your doctor, on the other hand, has the authority to make an exception.

You should only take Morphine if your doctor thinks it's absolutely necessary while breastfeeding.

Morphine Injection Dosage
Follow your doctor's instructions very closely when taking Morphine. Always check with your doctor or pharmacist if you have any questions. Pain intensity and sensitivity determine dosage, which is determined by your doctor..

The tablets of morphine retard are taken with or between meals, with enough liquid, twice daily, at about the same time, with or without food. Divide, chew, or crush retard tablets at your own risk.

Put 10 ml (2 tsp) of water in the sachet that contains the Morphine 20 mg, 30 mg, or 60 mg retard suspension. Water is required to be added to the contents of both the 100 mg and 200 mg tablets in order to achieve a consistent solution. After about 10 seconds of vigorous mixing, strain into a glass and serve immediately. You can drink the rest of the contents of the glass if there are still some granules left.

After sprinkling the sachet's contents over cold, soft food, the contents can be consumed (eg yogurt, ice cream, baby food). Make sure you consume the entire sachet at once (e.g. sprinkled on a spoonful of soft food).

The normal dose at the start of therapy is two 10 mg retard tablets or the contents of one 20 mg sachet every 12 hours if you are under 70 kg in weight, old or physically weak. The dose is one retard tablet or the contents of one 30 mg sachet every 12 hours for people who weigh more than 70 kilograms. Your doctor may decide to gradually increase the dose if it's necessary.

The dosage schedule for children will be determined by the doctor based on the child's age and circumstances.

If you continue to have pain after stopping Morphine, call your doctor. In order to treat these breakthrough pains, your doctor may prescribe a quick-release pain reliever (back-up pain reliever).

Tell your doctor right away if you've taken more Morphine than recommended.

Stick to your doctor's recommended dosage schedule. It is critical to take the retard tablets or the retard suspension at regular intervals prescribed by your doctor if you want to have the best protection against pain or its recurrence. Do not wait until you experience pain again before taking the medication.

You should not alter the prescribed dosage on your own volition, as this could have serious consequences. Speak to your doctor or pharmacist if you believe the medication is acting too weakly or powerfully.

What side effects can Morphine have?


Very often, taking MORPHINE Continus can cause constipation. You can fight this ailment with a diet rich in fiber and with the intake of sufficient quantities of fluids, but often it will be necessary for the doctor to prescribe, in addition, a laxative.

Particularly at the beginning of therapy, nausea and vomiting can occur very frequently. If you feel sick or need to vomit, please tell your doctor, who may prescribe treatment.

In addition, the following side effects may occur when taking Morphine:

Frequent: decreased or loss of appetite, confusion, insomnia, dizziness, headache, involuntary muscle spasms, severe drowsiness or lightheadedness (sedation), abdominal pain, dry mouth, sweating, rash, itching, weakness, tiredness, malaise .

Occasional: hypersensitivity reactions, excitement, euphoria, hallucinations, mood changes, seizures, increased muscle tension, paraesthesia, visual disturbances, dizziness, palpitations, flushing of the face, drop in blood pressure, fainting (syncope), accumulation of fluids in the lungs (after a sudden increase in dosage), slowing and flattening of breathing (respiratory depression), impaired respiratory function, wheezing, bowel obstruction, taste disturbances, digestive disorders, increased liver values, itchy rash (hives), urinary retention, water retention (edema).

Acute general allergic reactions, thought disturbances, dysphoria, drug dependence, excessive sensitivity to pain (hyperalgesia), pain perception for stimuli that normally do not cause pain (allodynia), narrowing of the pupils, slow heart rate, decreased stimulus may also occur cough, changes in smell, pain in the gallbladder (biliary colic), absence of menstruation (amenorrhea), erectile disorders, decreased libido, habituation in case of prolonged use or withdrawal symptoms.

Morphine retard tablets 30 mg and 60 mg and Morphine suspension retard can cause hypersensitivity reactions of the skin and respiratory system, particularly in patients with asthma, urticaria, hypersensitivity to acetylsalicylic acids and other antirheumatic or analgesic agents.

Please note that, despite the absence of menstruation, it is possible for pregnancy to occur and therefore, even in the absence of menstruation, it is necessary to use an effective contraceptive during therapy with MORPHINE Continus.

In case of suspected overdose, immediately inform the doctor who will take the necessary countermeasures. Signs of overdose are: narrowing of the pupils, extreme slowing of breathing, low blood pressure, narcosis-like state.

Respiratory paralysis is the most serious danger related to overdose.

If you notice any side effects not described here you should inform your doctor or pharmacist.

What else needs to be taken into account?
Store at room temperature (15-25 ° C) and in a place inaccessible to children.

Once the treatment is complete, take the residual medicine to a collection point (doctor's office, pharmacy) for proper disposal.

The medicinal product should not be used beyond the date indicated with "EXP" on the container.

Your doctor or pharmacist, who have detailed professional information, can give you further information.

Also Sold Under
Trade NamesMS-Contin, oramorph SR, MSiR, Roxanol, Kadian, RMS,AVINZA, Duramorph
Duration of action
Action's duration3-5 HOURS
Onset of action 5 minutes (IV), 15 minutes (IM), 20 minutes (PO)
Clinical Information
Dependence Liabilityhigh
IndicationChronic Pain, Pain
Generic NameMorphine Sulphate

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